Contact Us
TEL: +86-571-89285568
Fax: +86-571-88830060
Website: www.z-light.com.cn
E-mail: tiffany@z-light.com.cn

Address: NO.111 Changda Road,Yuhang Economic Develpoment Zone,Hangzhou,China

Home > News > Content
Vandetanib Is Physicochemical
Jun 25, 2018

Vandetanib is physicochemical


Appearance and properties: white solid


Density: 1.406


Melting point: 240-243 DHS C


Boiling point: 538.2 absolute C at 760 mmHg


Flash: DHS 279.3 C


use


Anti-tumor materials.


The preparation methods


With 4 - hydroxy - 3 - methoxy benzoic acid ethyl ester as the starting material, through nitration, reduction, cyclization, substitution, reduction, aromatization chlorine - 4-6 - methoxy - 7 - (N - methyl - 4 - piperidine methoxy) quinazoline (A), with A 4 - bromine response to get goals - 2 - fluoro - aniline compounds everything he has.